Jong Hee Choi Selected Research

gintonin

5/2023	Gintonin, a Panax ginseng-derived LPA receptor ligand, attenuates kainic acid-induced seizures and neuronal cell death in the hippocampus via anti-inflammatory and anti-oxidant activities.
5/2021	Ginseng gintonin alleviates neurological symptoms in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis through lysophosphatidic acid 1 receptor.
4/2021	Ginseng gintonin attenuates the disruptions of brain microvascular permeability and microvascular endothelium junctional proteins in an APPswe/PSEN-1 double-transgenic mouse model of Αlzheimer's disease.
1/2021	Gintonin mitigates experimental autoimmune encephalomyelitis by stabilization of Nrf2 signaling via stimulation of lysophosphatidic acid receptors.
1/2019	Gintonin, a ginseng-derived ingredient, as a novel therapeutic strategy for Huntington's disease: Activation of the Nrf2 pathway through lysophosphatidic acid receptors.
1/2018	Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson's Disease via Lysophosphatidic Acid Receptors.

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Jong Hee Choi Research Topics

Disease

4	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2024 - 01/2015
4	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 01/2018
4	Demyelinating Diseases (Demyelinating Disease) 09/2023 - 01/2015
4	Parkinson Disease (Parkinson's Disease) 05/2023 - 01/2018
4	Huntington Disease (Huntington's Disease) 05/2023 - 01/2017
3	Multiple Sclerosis 01/2024 - 01/2015
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024 - 01/2021
2	Seizures (Absence Seizure) 05/2023 - 10/2016
2	Inflammation (Inflammations) 01/2023 - 01/2019
2	Pain (Aches) 11/2022 - 03/2016
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 11/2020 - 01/2018
1	Neuralgia (Stump Neuralgia) 11/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 11/2022
1	Hyperalgesia 11/2022
1	Cytokine Release Syndrome 05/2022
1	COVID-19 05/2022
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 05/2021
1	Amyloid Plaque 04/2021
1	Ovarian Cysts (Ovarian Cyst) 11/2020
1	Body Weight (Weight, Body) 01/2018
1	Nervous System Diseases (Neurological Disorders) 01/2018
1	Neuroinflammatory Diseases 01/2018
1	Hypertension (High Blood Pressure) 10/2016
1	Stroke (Strokes) 10/2016
1	Herpes Zoster 01/2015
1	Paralysis (Palsy) 01/2015

Drug/Important Bio-Agent (IBA)

7	Lysophosphatidic Acid ReceptorsIBA 05/2023 - 01/2018
6	gintoninIBA 05/2023 - 01/2018
4	Myelin-Oligodendrocyte GlycoproteinIBA 01/2024 - 01/2015
4	Neuroprotective AgentsIBA 01/2024 - 01/2018
3	Peptides (Polypeptides)IBA 01/2024 - 01/2015
3	LigandsIBA 05/2023 - 01/2019
3	AntioxidantsIBA 05/2023 - 07/2018
2	LipopolysaccharidesIBA 01/2024 - 01/2023
2	Kainic Acid (Kainate)IBA 05/2023 - 10/2016
2	CytokinesIBA 05/2022 - 01/2015
2	ChemokinesIBA 10/2021 - 01/2015
2	salicylhydroxamic acid (SHAM)IBA 10/2021 - 01/2021
2	lysophosphatidic acidIBA 05/2021 - 04/2021
2	Proteins (Proteins, Gene)FDA Link 04/2021 - 01/2018
2	Dehydroepiandrosterone (DHEA)IBA 11/2020 - 01/2018
2	Messenger RNA (mRNA)IBA 01/2018 - 01/2015
1	ginsenoside ReIBA 01/2024
1	CuprizoneIBA 09/2023
1	micrandilactone CIBA 01/2023
1	Conditioned Culture MediaIBA 01/2023
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2022
1	syringaresinolIBA 11/2022
1	molnupiravirIBA 05/2022
1	Antiviral Agents (Antivirals)IBA 05/2022
1	Ritonavir (Norvir)FDA Link 05/2022
1	nirmatrelvir and ritonavir drug combinationIBA 05/2022
1	nirmatrelvirIBA 05/2022
1	NADPH Oxidase 2IBA 05/2021
1	Cholinergic Agents (Cholinergics)IBA 04/2021
1	Evans Blue (Blue, Evans)FDA Link 04/2021
1	Testosterone (Sustanon)FDA Link 11/2020
1	Estradiol (Delestrogen)FDA LinkGeneric 11/2020
1	kyung-ok-koIBA 01/2018
1	Prostaglandins EIBA 01/2018
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2018
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2018
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2018
1	3-nitropropionic acidIBA 01/2017
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 03/2016
1	NF-kappa B (NF-kB)IBA 03/2016
1	Formaldehyde (Formol)FDA Link 03/2016
1	Chemokine CCL5IBA 01/2015
1	Claudin-5IBA 01/2015
1	Claudin-3IBA 01/2015

Therapy/Procedure

2	East Asian Traditional Medicine (Oriental Medicine) 10/2016 - 01/2015
1	Spinal Injections 11/2022
1	Oral Administration 04/2021